APH 2004, 62, 185-196:
The validity of the Frail instrument in General Practice.
J. De Lepeleire, M. Ylieff, J. Stessens, F. Buntinx, L. Paquay
Keywords: Frail Elderly, Diagnosis, Dementia
Aims: The frailty concept is of growing importance. There is a need
for the development of a generic instrument to fasten down clinicians’ judgment
about the autonomy and the degree of frailty of the elderly. It can be
a worthwhile tool in the early detection of dementia in primary health care.
Methods: The validity of the Frail instrument was tested.
Out of the Qualidem study population, for 553 persons a Camdex-R
score and MMSE are available to test the diagnostic parameters.
Second, using data of 845 subjects at home and in the homes for the
elderly, validity has been studied by the non linear explorative principal
component analysis using Princals.
Results: The diagnostic parameters of the Frail test in single use
and in combination with MMSE for 553 persons are good. Sensitivity is
good but specificity is weak. A good Oddsratio is significantly higher
when it is used combining Frail with MMSE.
The three dimensions of the PRINCALS analysis explained 72% of all
variance. The component loadings express the strength of association
between each of the items on the one hand and the identified component
(i.e. dimension) on the other.
Conclusion: The Frail instrument has a good diagnostic value. There
are strong arguments for a good content validity of the instrument.