APH 1999, 57, 343-355:
of 5000 patients observed at a respiratory department of a general
hospital in Flanders (Belgium).
L. Siemons, B. Standaerd, P. Wahlen, and Ph. Van Wilder
Keywords: asthma, bronchoscopy, COPD, hospitalisation, lung cancer, smoking
|Objective: An observational study was carried out with patients attending the pneumology department of the St-Jozef Clinic in order to analyse the relationship between disease incidence, hospitalisation and bronchoscopic examination and the risk factors age, gender and smoking habits.
Methods: More than 5000 patients (ambulatory or hospitalised) were enrolled from 1991 until 1996.
Results: Sex distribution was male n = 3286 (57.2%),
female n 2456 (42.8%). The incidence of the major diseases was as follows: chronic obstructive
pulmonary disease (COPD) n = 1693 (29.5%); asthma n = 1003 (17.5%); lung cancer n = 295 (5.1%).
Current or ex-smoking resulted in an odds ratio for lung cancer of 32.8 (95% C.I.: 12.2 - 88.5). The lung carcinoma sex ratio was 8.8
male to female. The histological examination of the lung carcinomas determined 52 patients suffered from small cell (17.6%), 65 from squamous
cell (22.0%), 66 from adenocarcinoma (22.41%), 111 (37.601o) from non-small other and 1 (0. 3%) from mixed type lung cancer. Lung cancer and COPD,
male patients and patients with smoking habits significantly increased the occurrence of hospitalisation and the need for bronchoscopic examinations.