APH 1999, 57, 275-286:

Chlamydia pneumoniae: review and possible link with arteriosclerosis ?

M. Ieven

Keywords: chlamydia pneumoniae, diagnosis, epidemiology, link with atherosclerosis

Chlamydia pneumoniae was recognised as a third species in the genus Chlamydia in 1989. It is responsible for about 10% of pneumonia and for less severe forms of respiratory infections such as bronchitis and asthma. During recent years, seroepidemiologic studies showed a relation between coronary arteriosclerosis and C. pneumoniae infections. In 1992 Shor et al. detected for the first time C. pneumoniae in atheromatous lesions by electron microscopy. During the following years the organism was detected by several techniques in diseased artery walls. However, this does not prove a causal relationship. This presentation gives an overview on the diagnosis and clinical significance of C. pneumoniae and its possible role in atherosclerosis.